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kobas for kegg analysis software  (Novogene)

 
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    Structured Review

    Novogene kobas for kegg analysis software
    Functional analyses of target genes of DEMs (A) Sankey diagram analysis of predicted DEMs targets. (B) GO enrichment analysis of predicted target genes of up-regulated DEMs. (C) <t>KEGG</t> analysis of predicted target genes of up-regulated DEMs.
    Kobas For Kegg Analysis Software, supplied by Novogene, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/kobas+software/pmc12906189-53-33-47?v=Novogene
    Average 86 stars, based on 1 article reviews
    kobas for kegg analysis software - by Bioz Stars, 2026-07
    86/100 stars

    Images

    1) Product Images from "miRNA profiling reveals that gga-let-7i/COL1A2 axis induces cell cycle arrest and triggers cellular senescence to accelerate ovarian aging in laying hens by suppressing the PI3K/AKT/MDM2 pathway"

    Article Title: miRNA profiling reveals that gga-let-7i/COL1A2 axis induces cell cycle arrest and triggers cellular senescence to accelerate ovarian aging in laying hens by suppressing the PI3K/AKT/MDM2 pathway

    Journal: Poultry Science

    doi: 10.1016/j.psj.2026.106542

    Functional analyses of target genes of DEMs (A) Sankey diagram analysis of predicted DEMs targets. (B) GO enrichment analysis of predicted target genes of up-regulated DEMs. (C) KEGG analysis of predicted target genes of up-regulated DEMs.
    Figure Legend Snippet: Functional analyses of target genes of DEMs (A) Sankey diagram analysis of predicted DEMs targets. (B) GO enrichment analysis of predicted target genes of up-regulated DEMs. (C) KEGG analysis of predicted target genes of up-regulated DEMs.

    Techniques Used: Functional Assay

    Prediction and validation of gga-let-7i target genes. (A) The target genes of gga-let-7i were predicted by Targetscan, Diana and miRDB data bases. (B) Top 25 of KEGG enrichment of predicted gga-let-7i target genes. (C and D) Expression of alternative gga-let-7i target gene in response to gga-let-7i overexpression and inhibition, n = 9. (E) Binding site between gga-let-7i and COL1A2 was predicted by RNAhybird. (F) Schematic diagram depicting the design of the gga-let-7i/COL1A2 dual-luciferase reporter assay. (G) Dual-luciferase reporter assay showed that gga-let-7i directly binds to 3′UTR region of COL1A2, n = 3. All data were derived from at least three independent replicates and are presented as the mean ± SEM. *, P < 0.05; ⁎⁎ , P < 0.01.
    Figure Legend Snippet: Prediction and validation of gga-let-7i target genes. (A) The target genes of gga-let-7i were predicted by Targetscan, Diana and miRDB data bases. (B) Top 25 of KEGG enrichment of predicted gga-let-7i target genes. (C and D) Expression of alternative gga-let-7i target gene in response to gga-let-7i overexpression and inhibition, n = 9. (E) Binding site between gga-let-7i and COL1A2 was predicted by RNAhybird. (F) Schematic diagram depicting the design of the gga-let-7i/COL1A2 dual-luciferase reporter assay. (G) Dual-luciferase reporter assay showed that gga-let-7i directly binds to 3′UTR region of COL1A2, n = 3. All data were derived from at least three independent replicates and are presented as the mean ± SEM. *, P < 0.05; ⁎⁎ , P < 0.01.

    Techniques Used: Biomarker Discovery, Expressing, Over Expression, Inhibition, Binding Assay, Luciferase, Reporter Assay, Derivative Assay



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    Image Search Results


    Functional analyses of target genes of DEMs (A) Sankey diagram analysis of predicted DEMs targets. (B) GO enrichment analysis of predicted target genes of up-regulated DEMs. (C) KEGG analysis of predicted target genes of up-regulated DEMs.

    Journal: Poultry Science

    Article Title: miRNA profiling reveals that gga-let-7i/COL1A2 axis induces cell cycle arrest and triggers cellular senescence to accelerate ovarian aging in laying hens by suppressing the PI3K/AKT/MDM2 pathway

    doi: 10.1016/j.psj.2026.106542

    Figure Lengend Snippet: Functional analyses of target genes of DEMs (A) Sankey diagram analysis of predicted DEMs targets. (B) GO enrichment analysis of predicted target genes of up-regulated DEMs. (C) KEGG analysis of predicted target genes of up-regulated DEMs.

    Article Snippet: Gene Ontology ( GO ) enrichment and Kyoto Encyclopedia of Genes and Genomes ( KEGG ) pathway analysis were conducted on the target gene candidates of DEMs through ClusterProfile (for GO analysis) and KOBAS (for KEGG analysis) software. miRNA library construction and deep sequencing were performed by Novogene (Beijing, China).

    Techniques: Functional Assay

    Prediction and validation of gga-let-7i target genes. (A) The target genes of gga-let-7i were predicted by Targetscan, Diana and miRDB data bases. (B) Top 25 of KEGG enrichment of predicted gga-let-7i target genes. (C and D) Expression of alternative gga-let-7i target gene in response to gga-let-7i overexpression and inhibition, n = 9. (E) Binding site between gga-let-7i and COL1A2 was predicted by RNAhybird. (F) Schematic diagram depicting the design of the gga-let-7i/COL1A2 dual-luciferase reporter assay. (G) Dual-luciferase reporter assay showed that gga-let-7i directly binds to 3′UTR region of COL1A2, n = 3. All data were derived from at least three independent replicates and are presented as the mean ± SEM. *, P < 0.05; ⁎⁎ , P < 0.01.

    Journal: Poultry Science

    Article Title: miRNA profiling reveals that gga-let-7i/COL1A2 axis induces cell cycle arrest and triggers cellular senescence to accelerate ovarian aging in laying hens by suppressing the PI3K/AKT/MDM2 pathway

    doi: 10.1016/j.psj.2026.106542

    Figure Lengend Snippet: Prediction and validation of gga-let-7i target genes. (A) The target genes of gga-let-7i were predicted by Targetscan, Diana and miRDB data bases. (B) Top 25 of KEGG enrichment of predicted gga-let-7i target genes. (C and D) Expression of alternative gga-let-7i target gene in response to gga-let-7i overexpression and inhibition, n = 9. (E) Binding site between gga-let-7i and COL1A2 was predicted by RNAhybird. (F) Schematic diagram depicting the design of the gga-let-7i/COL1A2 dual-luciferase reporter assay. (G) Dual-luciferase reporter assay showed that gga-let-7i directly binds to 3′UTR region of COL1A2, n = 3. All data were derived from at least three independent replicates and are presented as the mean ± SEM. *, P < 0.05; ⁎⁎ , P < 0.01.

    Article Snippet: Gene Ontology ( GO ) enrichment and Kyoto Encyclopedia of Genes and Genomes ( KEGG ) pathway analysis were conducted on the target gene candidates of DEMs through ClusterProfile (for GO analysis) and KOBAS (for KEGG analysis) software. miRNA library construction and deep sequencing were performed by Novogene (Beijing, China).

    Techniques: Biomarker Discovery, Expressing, Over Expression, Inhibition, Binding Assay, Luciferase, Reporter Assay, Derivative Assay